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20th Century Fox
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A Fantastic and Spectacular Voyage... Through the Human Body... Into the Brain.
In order to save an assassinated scientist, a submarine and its crew are shrunk to microscopic size and injected into his bloodstream.
CinemaSerf
Jan 6, 2026 · via TMDB
Back in the days of three-channel telly in Britain, this was one of the regular sci-fi staples that I really quite enjoyed as I grew up. It features “Messala” himself - Stephen Boyd, only this time he is being placed into a submarine with “Cora” (Raquel Welch) and “Michaels” (Donald Pleasence) and then shrunk. They are to be injected into the bloodstream of a scientist with a view to navigating his internal system, arriving at his brain and the using their laser to zap away a life-threatening blood clot. It appears that miniaturisation itself is no big deal, but after an hour the shrunken object starts to return to it’s normal size. The man they are hoping to assist is the only one who knows how to prolong that period and he had offered his knowledge to Uncle Sam before a car crash instigated by a foreign power had left him comatose. These intrepid travellers can’t be placed directly into his skull, so they are going to have to deal with the body’s formidable defences if they are to have any chance of saving his life. You also don’t have to be Einstein to figure out that one of their number isn’t sailing to the same chart, and it’s fairly obvious whom that is. Of course these are all a trusting team, so will anyone suspect before the mission is sabotaged? None of the acting here amounts to much, but the story offers us the visual effects folks an opportunity to create quite an exciting adventure whilst making our own innards looks distinctly inhospitable; there’s a zapper, some wobbly sets and some treachery too to keep it moving along after an admittedly slow first half hour. It’s not a great film but it has elements of innovation to it and like “This Island Earth” from 1955, it has a place amongst my childhood memories that I will always look upon fondly.
Peter McGinn
Feb 20, 2021 · via TMDB
I remember I really liked this movie when I was a teenager, along with the novel by Isaac Asimov that was based on the screenplay. (I never read the original story they based the screenplay on.) It was adventurous fun. I don’t recall if I was titillated by the presence on the cast of Raquel Welch, though they showed great restraint in having her covered up most of the time by the special submarine suit. I wasn’t as impressed or entertained watching it this time around. I thought there were a couple of plot holes and, needless to say, the special effects weren’t up to the standards we are used to after all these years. But I would still recommend it if you are interested in early science fiction films or if you are watching with children, for it is certainly suitable for all audiences.
John Chard
Jan 7, 2019 · via TMDB
Combined Miniature Deterrent Forces A medical and science crew board a submarine and are miniaturised and injected into an important foreign scientist's body. The mission is to remove a blood clot on his brain that was suffered during an assassination attempt. Once shrunk and in their new bodily world, the team must battle the body's defence systems as well as avoiding trouble with the major organs. Also on a clock of one hour before they return to normal size, they have to also contend with the fact there may be a saboteur on board. This be a fantastical voyage indeed... The crews voyage through the body's bloodstream and beyond is brought to life by the use of some splendidly inventive special effects, something which marks Fantastic Voyage out as one of the more visually appealing genre pictures of the time (winning Oscars for Best Colour Art Direction and for Best Visual Effects). It was also nominated for Best Cinematography, Best Editing and Best Sound Effects. It is in short a tip top tech credits production. Based on the novel written by Otto Klement and Jay Lewis Bixby, the story is both imaginative and totally fascinating from a biology viewpoint, which is something that helps offsets the somewhat staid performances from the cast. However, are we really watching this for thespian delights? No of course not. We want director Richard Fleischer to take us on a perilous journey through the human body, and maybe just give us some suspense into the bargain. That is achieved wholesale, and while the the ending is a little too rushed for comfort, this remains a silly but wonderful filmic experience. 7.5/10
User reviews courtesy of TMDB.
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Stephen Boyd
Grant
Raquel Welch
Cora
Edmond O'Brien
General Carter
Donald Pleasence
Dr. Michaels
Arthur O'Connell
Col. Donald Reid
William Redfield
Capt. Bill Owens
Arthur Kennedy
Dr. Duval
Jean Del Val
Jan Benes
Barry Coe
Communications Aide
Ken Scott
Secret Service
Shelby Grant
Nurse
James Brolin
Technician
Brendon Boone
Military Policeman (uncredited)
James Doohan
Dr. Sawyer (Hypothermia technician) (uncredited)
Kenneth MacDonald
Henry - Heart Monitoring (uncredited)
Christopher Riordan
Young Scientist (uncredited)
Dale Hennesy
Art Direction
Ernest Laszlo
Director of Photography
Richard Fleischer
Director
Saul David
Producer
Harper Goff
Researcher
Leonard Rosenman
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Jerome Bixby
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Bicara Cinta
2020
The Pied Pipers of Harlow
1965
Sign in to vote
Battle your watched movies head-to-head
Community Top Movies
Evil Dead II
1987 · 14 wins
The Dark Knight
2008 · 14 wins
Halloween
1978 · 13 wins
Final Destination
2000 · 12 wins
Halloween II
1981 · 11 wins
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